Endocardial-only catheter ablation with substantial improvement in ventricular fibrillation recurrences in a patient with Brugada syndrome

Introduction Brugada syndrome is known to be a life-threatening disease provoking lethal arrhythmias such as ventricular tachycardia/ventricular fibrillation (VF), but non–implantable cardioverter-defibrillator (ICD) treatment strategy remains a topic of discussion. Substrate-based catheter ablation of Brugada syndrome has been reported to be effective, but much is still unknown, for example, the relationship between local abnormal endocardial potentials and ablation results.